Product Data Sheet
BAY-298
Catalog No. A60672
BAY-298 is a selective luteinizing hormone receptor (LH-R) antagonist with an IC50 of 96 nM for human LH, 23 nM for rat LH, and 78 nM for cynomolgus monkey LH. This orally active compound effectively reduces sex hormone levels, making it a valuable tool for research focused on reproductive biology and endocrine regulation. Its specificity and potency position BAY-298 as a critical reagent for studies investigating LH-R signaling pathways and potential therapeutic applications in hormone-related disorders.
Chemical Information
| Catalog Num | A60672 |
|---|---|
| M. Wt | 473.93 |
| Formula | C27H21ClFN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2471978-97-7 |
| Synonyms | |
| SMILES | O=C(N1[C@@H](C2=CC=C(Cl)C=C2)C3=C(N=CC=C3)CC1)NC4=CC=C(OC5=CC=C(F)C=C5)C=C4 |
Biological Activity
| Description | BAY-298 is a selective luteinizing hormone receptor (LH-R) antagonist with an IC50 of 96 nM for human LH, 23 nM for rat LH, and 78 nM for cynomolgus monkey LH. This orally active compound effectively reduces sex hormone levels, making it a valuable tool for research focused on reproductive biology and endocrine regulation. Its specificity and potency position BAY-298 as a critical reagent for studies investigating LH-R signaling pathways and potential therapeutic applications in hormone-related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
