Product Data Sheet
GnRH-R antagonist 1
Catalog No. A60697
GnRH-R antagonist 1 is a potent GnRH receptor antagonist that exhibits high binding affinity with an IC50 of 0.57 nM and strong in vitro antagonistic activity at an IC50 of 2.18 nM. This compound is membrane-permeable and orally bioavailable, making it suitable for various research applications. It is particularly valuable in studies focused on advanced prostate cancer and in investigating the prevention of premature luteinizing hormone peaks.
Chemical Information
| Catalog Num | A60697 |
|---|---|
| M. Wt | 721.65 |
| Formula | C31H28F5N7O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2826273-90-7 |
| Synonyms | |
| SMILES | O=C(NOC)NC1=CC=C(C(S2)=C(CN(C)CCOC(F)(F)F)C(C(N3C4=NN=C(OC)C=C4)=O)=C2N(CC5=C(F)C=CC=C5F)C3=O)C=C1 |
Biological Activity
| Description | GnRH-R antagonist 1 is a potent GnRH receptor antagonist that exhibits high binding affinity with an IC50 of 0.57 nM and strong in vitro antagonistic activity at an IC50 of 2.18 nM. This compound is membrane-permeable and orally bioavailable, making it suitable for various research applications. It is particularly valuable in studies focused on advanced prostate cancer and in investigating the prevention of premature luteinizing hormone peaks. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
