Product Data Sheet
GnRH-R antagonist-2
Catalog No. A60751
GnRH-R Antagonist-2 is a selective antagonist of the Gonadotropin-Releasing Hormone Receptor (GnRH-R), exhibiting IC50 values of 43 nM for rat and 88 nM for human receptors. This compound is pivotal in studying hormone-dependent conditions, such as endometriosis and breast and prostate cancers. Its specificity makes it a valuable tool for elucidating the roles of GnRH signaling in various biological contexts and developing targeted therapies.
Chemical Information
| Catalog Num | A60751 |
|---|---|
| M. Wt | 630.88 |
| Formula | C37H50N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1000819-21-5 |
| Synonyms | |
| SMILES | O=C(C1CCN(CC1C)CCC2=C(C3=CC(C)=CC(C)=C3)NC4=C2C=C(C(C)(C)C(N5C6CCC5CC6)=O)S4)N7CCOCC7 |
Biological Activity
| Description | GnRH-R Antagonist-2 is a selective antagonist of the Gonadotropin-Releasing Hormone Receptor (GnRH-R), exhibiting IC50 values of 43 nM for rat and 88 nM for human receptors. This compound is pivotal in studying hormone-dependent conditions, such as endometriosis and breast and prostate cancers. Its specificity makes it a valuable tool for elucidating the roles of GnRH signaling in various biological contexts and developing targeted therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
