Product Data Sheet

RS-18286

Catalog No. A60755

main product photo
RS-18286 is a potent luteinizing hormone-releasing hormone (LHRH) antagonist that effectively blocks the pituitary LHRH receptor. By inhibiting this receptor, RS-18286 suppresses the secretion of luteinizing hormone (LH) from the pituitary gland, leading to decreased serum levels of gonadal steroids. This compound can be utilized in research applications related to reproductive biology and endocrinology.
Chemical Information
Catalog NumA60755
M. Wt1523.61
FormulaC74H101Cl2N17O14
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.109458-76-6
Synonyms
SMILESC([C@@H](NC([C@@H](CC1=CC=C(Cl)C=C1)NC([C@@H](CC2=CC=C(Cl)C=C2)NC(C)=O)=O)=O)C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@@H](C(O)=O)C)=O)CCC4)CCCNC(=N)N)=O)CC(C)C)=O)CCCCN=C(NCC)NCC)=O)=O)CO)=O)C=5C=6C(NC5)=CC=CC6
Biological Activity
DescriptionRS-18286 is a potent luteinizing hormone-releasing hormone (LHRH) antagonist that effectively blocks the pituitary LHRH receptor. By inhibiting this receptor, RS-18286 suppresses the secretion of luteinizing hormone (LH) from the pituitary gland, leading to decreased serum levels of gonadal steroids. This compound can be utilized in research applications related to reproductive biology and endocrinology.
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