Product Data Sheet
GPR109 receptor agonist-3
Catalog No. A60773
GPR109 receptor agonist-3 is an orally active compound that selectively targets and activates the GPR109 receptor, exhibiting an IC50 of 310 nM. This agonist demonstrates significant antioxidative and cytoprotective properties similar to Lipoic acid. In preclinical studies, GPR109 receptor agonist-3 effectively reduces total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while increasing high-density lipoprotein cholesterol in high-fat diet-fed rats. It serves as a valuable tool for investigating the mechanisms underlying atherosclerosis and lipid metabolism.
Chemical Information
| Catalog Num | A60773 |
|---|---|
| M. Wt | 353.50 |
| Formula | C16H23N3O2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 944559-31-3 |
| Synonyms | |
| SMILES | O=C(C1=CC=CN=C1)NCCNC(CCCCC2SSCC2)=O |
Biological Activity
| Description | GPR109 receptor agonist-3 is an orally active compound that selectively targets and activates the GPR109 receptor, exhibiting an IC50 of 310 nM. This agonist demonstrates significant antioxidative and cytoprotective properties similar to Lipoic acid. In preclinical studies, GPR109 receptor agonist-3 effectively reduces total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while increasing high-density lipoprotein cholesterol in high-fat diet-fed rats. It serves as a valuable tool for investigating the mechanisms underlying atherosclerosis and lipid metabolism. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
