Product Data Sheet
DA-1241
Catalog No. A60780
DA-1241 is a selective agonist of the GPR119 receptor. It effectively inhibits macrophage differentiation by downregulating NFκB signaling pathways through GPR119 activation. Additionally, DA-1241 demonstrates potential in conjunction with DPP4 inhibitors to alleviate liver inflammation and normalize inflammation-related gene expression in the liver. This compound is primarily utilized in research focused on metabolic dysfunction-associated steatohepatitis (MASH).
Chemical Information
| Catalog Num | A60780 |
|---|---|
| M. Wt | 471.54 |
| Formula | C25H31F2N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1914136-10-9 |
| Synonyms | |
| SMILES | CC(C1=NC(C2=C(F)C=C(OCCCC3CCN(C4=NC=C(CC)C=N4)CC3)C=C2F)=NO1)C |
Biological Activity
| Description | DA-1241 is a selective agonist of the GPR119 receptor. It effectively inhibits macrophage differentiation by downregulating NFκB signaling pathways through GPR119 activation. Additionally, DA-1241 demonstrates potential in conjunction with DPP4 inhibitors to alleviate liver inflammation and normalize inflammation-related gene expression in the liver. This compound is primarily utilized in research focused on metabolic dysfunction-associated steatohepatitis (MASH). |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
