Product Data Sheet
AS-1669058
Catalog No. A60794
AS-1669058 is a selective agonist of the GPR119 receptor, showing promise in the management of type 2 diabetes. This compound enhances insulin secretion in response to elevated blood glucose levels both in vitro and in vivo, while also stimulating insulin promoter activity. In studies using db/db mice, AS-1669058 demonstrated significant improvements in glucose tolerance and reductions in blood glucose levels, indicating its potential utility in diabetes research.
Chemical Information
| Catalog Num | A60794 |
|---|---|
| M. Wt | 511.27 |
| Formula | C20H17BrF2N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1395553-32-8 |
| Synonyms | |
| SMILES | CC1=CC(NCCC2=C[N+]([O-])=CC=C2)=NC(C3=CC(F)=C(Br)C=C3F)=N1.O=C(O)C(O)=O |
Biological Activity
| Description | AS-1669058 is a selective agonist of the GPR119 receptor, showing promise in the management of type 2 diabetes. This compound enhances insulin secretion in response to elevated blood glucose levels both in vitro and in vivo, while also stimulating insulin promoter activity. In studies using db/db mice, AS-1669058 demonstrated significant improvements in glucose tolerance and reductions in blood glucose levels, indicating its potential utility in diabetes research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
