Product Data Sheet
Diethyl-Lodoxamide
Catalog No. A60811
Diethyl-Lodoxamide is a potent agonist of the GPR35 receptor, demonstrating significant potential for the treatment of inflammatory bowel disease. It activates GPR35 in human, mouse, and rat models, exhibiting similar EC50 values across these species. Notably, Diethyl-Lodoxamide has been shown to alleviate clinical symptoms in DSS-induced mouse models of inflammatory bowel disease, offering a more effective solution compared to traditional therapies such as 5-ASA. The compound's pharmaceutical properties have been carefully optimized to align with advanced drug design requirements.
Chemical Information
| Catalog Num | A60811 |
|---|---|
| M. Wt | 367.74 |
| Formula | C15H14ClN3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 53882-13-6 |
| Synonyms | |
| SMILES | N#CC1=CC(NC(C(OCC)=O)=O)=C(Cl)C(NC(C(OCC)=O)=O)=C1 |
Biological Activity
| Description | Diethyl-Lodoxamide is a potent agonist of the GPR35 receptor, demonstrating significant potential for the treatment of inflammatory bowel disease. It activates GPR35 in human, mouse, and rat models, exhibiting similar EC50 values across these species. Notably, Diethyl-Lodoxamide has been shown to alleviate clinical symptoms in DSS-induced mouse models of inflammatory bowel disease, offering a more effective solution compared to traditional therapies such as 5-ASA. The compound's pharmaceutical properties have been carefully optimized to align with advanced drug design requirements. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
