Product Data Sheet

GPR52 antagonist-1

Catalog No. A60815

main product photo
GPR52 antagonist-1 is a selective antagonist of the GPR52 receptor, exhibiting an IC50 of 0.63 μM. This compound effectively reduces levels of the mutant huntingtin protein (mHTT) and supports the survival of mouse primary striatal neurons. GPR52 antagonist-1 is important for research applications investigating neurodegenerative disorders, particularly Huntington's disease, and offers insights into the role of GPR52 in neuronal health.
Chemical Information
Catalog NumA60815
M. Wt242.34
FormulaC15H14OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1239987-91-7
Synonyms
SMILESO=C(C1=CC=CS1)/C=C/CCC2=CC=CC=C2
Biological Activity
DescriptionGPR52 antagonist-1 is a selective antagonist of the GPR52 receptor, exhibiting an IC50 of 0.63 μM. This compound effectively reduces levels of the mutant huntingtin protein (mHTT) and supports the survival of mouse primary striatal neurons. GPR52 antagonist-1 is important for research applications investigating neurodegenerative disorders, particularly Huntington's disease, and offers insights into the role of GPR52 in neuronal health.
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