Product Data Sheet
ML-184
Catalog No. A60821
ML-184 is a selective agonist for the GPR55 receptor, exhibiting an EC50 value of 250 nM and demonstrating over 100-fold selectivity for GPR55 compared to GPR35, CB1, and CB2. This compound triggers phosphorylation of ERK1/2 and facilitates the translocation of PKCβII to the plasma membrane through GPR55 activation. Additionally, ML-184 enhances the proliferation of neural stem cells and promotes neuronal differentiation in vitro, making it a valuable tool for research in neurobiology and cellular signaling pathways.
Chemical Information
| Catalog Num | A60821 |
|---|---|
| M. Wt | 470.63 |
| Formula | C25H34N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 794572-10-4 |
| Synonyms | CID2440433 |
| SMILES | CC1=CC=CC(N2CCN(CC2)C(C3=CC(S(N(C)C)(=O)=O)=CC=C3N4CCCC4)=O)=C1C |
Biological Activity
| Description | ML-184 is a selective agonist for the GPR55 receptor, exhibiting an EC50 value of 250 nM and demonstrating over 100-fold selectivity for GPR55 compared to GPR35, CB1, and CB2. This compound triggers phosphorylation of ERK1/2 and facilitates the translocation of PKCβII to the plasma membrane through GPR55 activation. Additionally, ML-184 enhances the proliferation of neural stem cells and promotes neuronal differentiation in vitro, making it a valuable tool for research in neurobiology and cellular signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
