Product Data Sheet
MS48107
Catalog No. A60835
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). This compound exhibits high selectivity for GPR68, minimizing off-target effects on related proton GPCRs, neurotransmitter transporters, and hERG ion channels. Additionally, MS48107 demonstrates the ability to effectively cross the blood-brain barrier in murine models, making it a valuable tool for neurobiological research and studies involving GPR68-related pathways.
Chemical Information
| Catalog Num | A60835 |
|---|---|
| M. Wt | 417.44 |
| Formula | C23H20FN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2375070-79-2 |
| Synonyms | |
| SMILES | OCC1=CC=CC(F)=C1C2=NC(N)=NC(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=N2 |
Biological Activity
| Description | MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). This compound exhibits high selectivity for GPR68, minimizing off-target effects on related proton GPCRs, neurotransmitter transporters, and hERG ion channels. Additionally, MS48107 demonstrates the ability to effectively cross the blood-brain barrier in murine models, making it a valuable tool for neurobiological research and studies involving GPR68-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
