Product Data Sheet

RTI-122

Catalog No. A60856

main product photo
RTI-122 is a potent agonist of the GPR88 receptor, demonstrating effective brain penetration and a half-life of 5.8 hours in murine models. This compound exhibits a cAMP EC50 value of 11 nM, making it a valuable tool for investigating mechanisms associated with excessive drinking behaviors. Its metabolic stability and selective activity position RTI-122 as a significant reagent for research in addiction neuroscience and related fields.
Chemical Information
Catalog NumA60856
M. Wt491.60
FormulaC29H34FN3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3034664-39-3
Synonyms
SMILESCO[C@H](C)[C@H](N)CN(C1=CC=C(C2=CC=C(C=C2)OC(C)C)C=C1)C([C@H]3[C@H](C4=CC=C(C=N4)F)C3)=O
Biological Activity
DescriptionRTI-122 is a potent agonist of the GPR88 receptor, demonstrating effective brain penetration and a half-life of 5.8 hours in murine models. This compound exhibits a cAMP EC50 value of 11 nM, making it a valuable tool for investigating mechanisms associated with excessive drinking behaviors. Its metabolic stability and selective activity position RTI-122 as a significant reagent for research in addiction neuroscience and related fields.
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