Product Data Sheet

Cenderitide

Catalog No. A60866

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Cenderitide is a potent agonist of particulate guanylyl cyclase receptors (pGC). This natriuretic peptide, composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP), activates pGC-A and pGC-B, leading to increased levels of the second messenger cGMP. Cenderitide effectively suppresses aldosterone production and helps preserve glomerular filtration rate (GFR) without causing a reduction in blood pressure. It is suitable for research applications focused on heart failure.
Chemical Information
Catalog NumA60866
M. Wt3745.27
FormulaC158H263N49O50S3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.507289-11-4
Synonyms
SMILES
Biological Activity
DescriptionCenderitide is a potent agonist of particulate guanylyl cyclase receptors (pGC). This natriuretic peptide, composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP), activates pGC-A and pGC-B, leading to increased levels of the second messenger cGMP. Cenderitide effectively suppresses aldosterone production and helps preserve glomerular filtration rate (GFR) without causing a reduction in blood pressure. It is suitable for research applications focused on heart failure.
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