Product Data Sheet
SGC agonist 2
Catalog No. A60882
SGC Agonist 2 is a selective agonist of soluble guanylate cyclase (SGC), an essential enzyme in the nitric oxide (NO) signaling pathway that produces cyclic GMP (cGMP). This compound demonstrates significant biological activity in modulating vasodilation and has implications for research into cardiovascular diseases, including heart failure, pulmonary hypertension, angina, and myocardial infarction, as well as fibrotic conditions such as renal fibrosis and systemic sclerosis. Its utility in investigating these pathologies makes SGC Agonist 2 a valuable tool for advancing cardiovascular and fibrosis-related research.
Chemical Information
| Catalog Num | A60882 |
|---|---|
| M. Wt | 461.42 |
| Formula | C23H17F2N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2735713-77-4 |
| Synonyms | |
| SMILES | O=C1[C@]2([H])C3=C(N1)NC(C(C4=C5)=NN(CC6=C(C=CC=C6)F)C4=NC=C5F)=NC3=NC(C2(C)C)=O |
Biological Activity
| Description | SGC Agonist 2 is a selective agonist of soluble guanylate cyclase (SGC), an essential enzyme in the nitric oxide (NO) signaling pathway that produces cyclic GMP (cGMP). This compound demonstrates significant biological activity in modulating vasodilation and has implications for research into cardiovascular diseases, including heart failure, pulmonary hypertension, angina, and myocardial infarction, as well as fibrotic conditions such as renal fibrosis and systemic sclerosis. Its utility in investigating these pathologies makes SGC Agonist 2 a valuable tool for advancing cardiovascular and fibrosis-related research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
