Product Data Sheet

SE 175

Catalog No. A60891

main product photo
SE 175 is an organic nitrate compound that functions as a nitric oxide (NO) donor through the reductive conversion of its nitrate group. Its primary mechanism involves the stimulation of endothelial soluble guanylate cyclase, resulting in pronounced aortic vasorelaxation, with an EC50 value of 0.20 µM. This compound is valuable for research investigating vascular biology and cardiovascular function, particularly in studies related to NO-mediated signaling pathways.
Chemical Information
Catalog NumA60891
M. Wt347.34
FormulaC16H13NO6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.258278-64-7
Synonyms
SMILESO=C(OC)C1=CC=CC=C1SC(C2=CC=C(CO[N+]([O-])=O)C=C2)=O
Biological Activity
DescriptionSE 175 is an organic nitrate compound that functions as a nitric oxide (NO) donor through the reductive conversion of its nitrate group. Its primary mechanism involves the stimulation of endothelial soluble guanylate cyclase, resulting in pronounced aortic vasorelaxation, with an EC50 value of 0.20 µM. This compound is valuable for research investigating vascular biology and cardiovascular function, particularly in studies related to NO-mediated signaling pathways.
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