Product Data Sheet
Formycin triphosphate
Catalog No. A60897
Formycin triphosphate is a fluorescent analog of ATP, designed to bind to enzyme active sites and exhibit enhanced fluorescence. It acts as an ATP-competitive inhibitor of chicken liver pyruvate carboxylase, enabling the study of ATP-dependent pathways. Additionally, Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 of approximately 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 μM, making it valuable for research in cellular signaling and metabolic regulation.
Chemical Information
| Catalog Num | A60897 |
|---|---|
| M. Wt | 507.18 |
| Formula | C10H16N5O13P3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 16409-13-5 |
| Synonyms | |
| SMILES | NC1=C2C(C([C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)=NN2)=NC=N1 |
Biological Activity
| Description | Formycin triphosphate is a fluorescent analog of ATP, designed to bind to enzyme active sites and exhibit enhanced fluorescence. It acts as an ATP-competitive inhibitor of chicken liver pyruvate carboxylase, enabling the study of ATP-dependent pathways. Additionally, Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 of approximately 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 of around 100 μM, making it valuable for research in cellular signaling and metabolic regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
