Product Data Sheet

ICMT-IN-18

Catalog No. A60935

main product photo
ICMT-IN-18 is a potent inhibitor of isoprenylcysteine carboxymethyltransferase (ICMT), demonstrating an IC50 of 0.066 μM. This compound is valuable for investigating the role of ICMT in post-translational modifications and protein processing. Its applications extend to studies of cancer biology and signal transduction pathways where altered protein function may influence disease progression.
Chemical Information
Catalog NumA60935
M. Wt334.45
FormulaC22H26N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1313602-81-1
Synonyms
SMILESN#CC1=CC=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=C1
Biological Activity
DescriptionICMT-IN-18 is a potent inhibitor of isoprenylcysteine carboxymethyltransferase (ICMT), demonstrating an IC50 of 0.066 μM. This compound is valuable for investigating the role of ICMT in post-translational modifications and protein processing. Its applications extend to studies of cancer biology and signal transduction pathways where altered protein function may influence disease progression.
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