Product Data Sheet

ICMT-IN-22

Catalog No. A60953

main product photo
ICMT-IN-22 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.63 μM. This compound is instrumental in research applications related to lipid modification pathways, playing a crucial role in understanding post-translational modifications of proteins. Its use can facilitate studies on cellular signaling, protein stability, and the implications of ICMT activity in various diseases.
Chemical Information
Catalog NumA60953
M. Wt373.92
FormulaC22H28ClNO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1313603-09-6
Synonyms
SMILESCC(OCC1)(C)CC1(CCNC2=CC(OC)=CC=C2)C3=CC=C(Cl)C=C3
Biological Activity
DescriptionICMT-IN-22 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.63 μM. This compound is instrumental in research applications related to lipid modification pathways, playing a crucial role in understanding post-translational modifications of proteins. Its use can facilitate studies on cellular signaling, protein stability, and the implications of ICMT activity in various diseases.
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