Product Data Sheet

Spermatinamine

Catalog No. A60962

main product photo
Spermatinamine is a natural inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT). This novel alkaloid, characterized by its bromotyrosyl-spermine-bromotyrosyl sequence, exhibits significant biological activity affecting protein prenylation. It is derived from the Australian sponge Pseudoceratina and is useful in research applications investigating the roles of ICMT and protein modification pathways in cellular processes.
Chemical Information
Catalog NumA60962
M. Wt928.34
FormulaC32H44Br4N6O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1001438-81-8
Synonyms
SMILESBrC1=C(OC)C(Br)=CC(C/C(C(NCCCN(C)CCCCN(C)CCCNC(/C(CC2=CC(Br)=C(OC)C(Br)=C2)=N/O)=O)=O)=N\O)=C1
Biological Activity
DescriptionSpermatinamine is a natural inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT). This novel alkaloid, characterized by its bromotyrosyl-spermine-bromotyrosyl sequence, exhibits significant biological activity affecting protein prenylation. It is derived from the Australian sponge Pseudoceratina and is useful in research applications investigating the roles of ICMT and protein modification pathways in cellular processes.
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