Product Data Sheet

Ritolukast

Catalog No. A60991

main product photo
Ritolukast is a potent antagonist of the LTD4/E4 leukotriene receptors. This compound demonstrates significant biological activity by inhibiting bronchoconstriction induced by aerosolized LTD4, with an ID50 of 0.5 mg/kg in guinea pigs. Ritolukast is primarily utilized in research applications related to respiratory pharmacology and the study of allergic inflammatory responses.
Chemical Information
Catalog NumA60991
M. Wt382.36
FormulaC17H13F3N2O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.111974-60-8
SynonymsWy-48252
SMILESO=S(NC1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1)(C(F)(F)F)=O
Biological Activity
DescriptionRitolukast is a potent antagonist of the LTD4/E4 leukotriene receptors. This compound demonstrates significant biological activity by inhibiting bronchoconstriction induced by aerosolized LTD4, with an ID50 of 0.5 mg/kg in guinea pigs. Ritolukast is primarily utilized in research applications related to respiratory pharmacology and the study of allergic inflammatory responses.
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