Product Data Sheet
BayCysLT2
Catalog No. A60994
BayCysLT2 is a selective and potent antagonist of the cysteinyl leukotriene 2 (CysLT2) receptor, exhibiting an IC50 value of 53 nM. It effectively inhibits calcium mobilization induced by leukotriene D4 in HEK293 cells expressing human CysLT2 receptors. Additionally, BayCysLT2 demonstrates the ability to reverse LTC4-induced increases in coronary artery perfusion pressure and decreases in contractility in isolated guinea pig hearts, making it valuable for research on cardiovascular and inflammatory responses.
Chemical Information
| Catalog Num | A60994 |
|---|---|
| M. Wt | 589.68 |
| Formula | C34H39NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 712313-33-2 |
| Synonyms | |
| SMILES | OC(C1=CC=C(OCCCC2=CC=C(C=C2)OCCCCOC3=CC=CC=C3)C(C(NC4CC(C(O)=O)CCC4)=O)=C1)=O |
Biological Activity
| Description | BayCysLT2 is a selective and potent antagonist of the cysteinyl leukotriene 2 (CysLT2) receptor, exhibiting an IC50 value of 53 nM. It effectively inhibits calcium mobilization induced by leukotriene D4 in HEK293 cells expressing human CysLT2 receptors. Additionally, BayCysLT2 demonstrates the ability to reverse LTC4-induced increases in coronary artery perfusion pressure and decreases in contractility in isolated guinea pig hearts, making it valuable for research on cardiovascular and inflammatory responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
