Product Data Sheet
SB-209247
Catalog No. A60998
SB-209247 is a selective leukotriene B4 (LTB4) receptor antagonist, exhibiting high affinity with a Ki of 0.78 nM. This compound effectively inhibits LTB4-induced calcium mobilization, with an IC50 of 6.6 nM, displaying significant anti-inflammatory properties. SB-209247 is valuable for research applications focusing on inflammatory diseases and the modulation of leukotriene signaling pathways.
Chemical Information
| Catalog Num | A60998 |
|---|---|
| M. Wt | 460.37 |
| Formula | C23H19Cl2NO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 154413-61-3 |
| Synonyms | |
| SMILES | O=C(O)/C=C/C1=NC(CSC2=C(Cl)C=CC=C2Cl)=CC=C1OCCC3=CC=CC=C3 |
Biological Activity
| Description | SB-209247 is a selective leukotriene B4 (LTB4) receptor antagonist, exhibiting high affinity with a Ki of 0.78 nM. This compound effectively inhibits LTB4-induced calcium mobilization, with an IC50 of 6.6 nM, displaying significant anti-inflammatory properties. SB-209247 is valuable for research applications focusing on inflammatory diseases and the modulation of leukotriene signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
