Product Data Sheet
Quininib
Catalog No. A61008
Quininib is a cysteinyl leukotriene 1 and 2 receptor antagonist, exhibiting IC50 values of 1.2 μM for CysLT1R and 52 μM for CysLT2R. This compound effectively inhibits developmental angiogenesis in the zebrafish eye model, making it a valuable tool for studying ocular neovascular pathologies. Quininib may serve as a complementary agent to existing anti-VEGF biological therapies in research applications focused on angiogenesis and related conditions.
Chemical Information
| Catalog Num | A61008 |
|---|---|
| M. Wt | 247.29 |
| Formula | C17H13NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 143816-42-6 |
| Synonyms | |
| SMILES | OC1=CC=CC=C1/C=C/C2=NC3=CC=CC=C3C=C2 |
Biological Activity
| Description | Quininib is a cysteinyl leukotriene 1 and 2 receptor antagonist, exhibiting IC50 values of 1.2 μM for CysLT1R and 52 μM for CysLT2R. This compound effectively inhibits developmental angiogenesis in the zebrafish eye model, making it a valuable tool for studying ocular neovascular pathologies. Quininib may serve as a complementary agent to existing anti-VEGF biological therapies in research applications focused on angiogenesis and related conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
