Product Data Sheet
LY 245769
Catalog No. A61027
LY 245769 is a leukotriene E4 (LTE4) inhibitor that functions as an omega-trifluoro analog. It exhibits inhibitory activity by interfering with the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4), with an IC50 value of 4 μM. This compound is essential for research on inflammatory processes and bronchoconstriction, contributing to the understanding of leukotriene signaling pathways and their role in respiratory diseases.
Chemical Information
| Catalog Num | A61027 |
|---|---|
| M. Wt | 550.64 |
| Formula | C25H33F3N8OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 127345-02-2 |
| Synonyms | |
| SMILES | O[C@@H](C1=CC=CC(C2=NN=NN2)=C1)[C@@H](/C=C/C=C\CCCCCCCCC(F)(F)F)SCCC3=NN=NN3 |
Biological Activity
| Description | LY 245769 is a leukotriene E4 (LTE4) inhibitor that functions as an omega-trifluoro analog. It exhibits inhibitory activity by interfering with the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4), with an IC50 value of 4 μM. This compound is essential for research on inflammatory processes and bronchoconstriction, contributing to the understanding of leukotriene signaling pathways and their role in respiratory diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
