Lipoxin B4 methyl ester
Catalog No. A61039

Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes.
Chemical Information
| Catalog Num | A61039 |
|---|---|
| M. Wt | 366.49 |
| Formula | C21H34O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 97589-07-6 |
| Synonyms | LXB4 methyl ester |
| SMILES | CCCCC[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)CCCC(OC)=O |
Biological Activity
| Description | Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


