Product Data Sheet

Lipoxin B4 methyl ester

Catalog No. A61039

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Lipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes.
Chemical Information
Catalog NumA61039
M. Wt366.49
FormulaC21H34O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.97589-07-6
SynonymsLXB4 methyl ester
SMILESCCCCC[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)CCCC(OC)=O
Biological Activity
DescriptionLipoxin B4 methyl ester is a lipid-soluble prodrug of the bioactive lipid mediator Lipoxin B4 (LXB4). It exhibits significant anti-inflammatory properties by inhibiting the migration and adhesion of polymorphonuclear leukocytes (PMNs) in response to leukotriene B4 (LTB4), with an IC50 value of 0.3 nM at concentrations as low as 100 nM. This compound serves as a valuable tool for research in inflammation and immune response studies, facilitating the exploration of LXB4's role in resolving inflammatory processes.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.