Product Data Sheet

JNJ-40929837

Catalog No. A61047

main product photo
JNJ-40929837 is a selective and orally active inhibitor of leukotriene A4 hydrolase (LTA4H). This compound effectively inhibits aminopeptidase activity, resulting in the accumulation of Pro-Gly-Pro in serum. JNJ-40929837 is primarily utilized in asthma research to explore its potential therapeutic effects and mechanisms of action related to inflammatory responses.
Chemical Information
Catalog NumA61047
M. Wt408.52
FormulaC22H24N4O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1191044-42-4
Synonyms
SMILESCC(N[C@@H](C[C@@]1([H])CC2)C[C@@]2([H])N1CC3=CC=C(C=C3)OC4=NC5=NC=CC=C5S4)=O
Biological Activity
DescriptionJNJ-40929837 is a selective and orally active inhibitor of leukotriene A4 hydrolase (LTA4H). This compound effectively inhibits aminopeptidase activity, resulting in the accumulation of Pro-Gly-Pro in serum. JNJ-40929837 is primarily utilized in asthma research to explore its potential therapeutic effects and mechanisms of action related to inflammatory responses.
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