Product Data Sheet
BLT2 antagonist-1
Catalog No. A61049
BLT2 antagonist-1 is a selective antagonist of the BLT2 receptor, demonstrated to inhibit the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM, while showing no effect on CHO-BLT1 cells. It also effectively inhibits the binding of leukotriene B4 (LTB4) to the BLT2 receptor, with a Ki value of 132 nM. This compound is valuable for research into inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Chemical Information
| Catalog Num | A61049 |
|---|---|
| M. Wt | 435.49 |
| Formula | C26H26FNO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2069220-61-5 |
| Synonyms | |
| SMILES | O=C(CCCC)N(C1=CC=CC(F)=C1)CC2=CC=C(C3=CC=C(OCC(O)=O)C=C3)C=C2 |
Biological Activity
| Description | BLT2 antagonist-1 is a selective antagonist of the BLT2 receptor, demonstrated to inhibit the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM, while showing no effect on CHO-BLT1 cells. It also effectively inhibits the binding of leukotriene B4 (LTB4) to the BLT2 receptor, with a Ki value of 132 nM. This compound is valuable for research into inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease (COPD). |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
