Product Data Sheet
MEN-91507
Catalog No. A61056
MEN-91507 is a potent orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLTR1). It effectively inhibits calcium transients induced by Leukotriene D4, exhibiting an insurmountable antagonistic behavior with a pKb of 10.25. MEN-91507 demonstrates significant efficacy in blocking Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea pig models. This compound is suitable for research applications in the fields of inflammation and immunology.
Chemical Information
| Catalog Num | A61056 |
|---|---|
| M. Wt | 482.51 |
| Formula | C28H23FN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 197506-04-0 |
| Synonyms | |
| SMILES | O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=C(F)C=C5)C=C4)C=CC=C13 |
Biological Activity
| Description | MEN-91507 is a potent orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLTR1). It effectively inhibits calcium transients induced by Leukotriene D4, exhibiting an insurmountable antagonistic behavior with a pKb of 10.25. MEN-91507 demonstrates significant efficacy in blocking Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea pig models. This compound is suitable for research applications in the fields of inflammation and immunology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
