Product Data Sheet
RG-7152
Catalog No. A61090
RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that enhances peroxisomal β-oxidation and promotes peroxisome bifunctional enzymes (PBEs) in hepatocytes across various animal models. Research indicates that RG-7152 significantly elevates PBE levels and β-oxidation activity in rat and mouse liver homogenates. Furthermore, comparative in vitro studies demonstrate its ability to induce PBEs similarly to clofibric acid, highlighting its potential utility in studying peroxisome proliferation and related metabolic pathways.
Chemical Information
| Catalog Num | A61090 |
|---|---|
| M. Wt | 361.40 |
| Formula | C20H19N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 107813-63-8 |
| Synonyms | |
| SMILES | C1(COC2=CC=CC(OCCCC3=NN=NN3)=C2)=NC4=CC=CC=C4C=C1 |
Biological Activity
| Description | RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that enhances peroxisomal β-oxidation and promotes peroxisome bifunctional enzymes (PBEs) in hepatocytes across various animal models. Research indicates that RG-7152 significantly elevates PBE levels and β-oxidation activity in rat and mouse liver homogenates. Furthermore, comparative in vitro studies demonstrate its ability to induce PBEs similarly to clofibric acid, highlighting its potential utility in studying peroxisome proliferation and related metabolic pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
