Product Data Sheet
Ricinelaidic acid
Catalog No. A61092
Ricinelaidic acid is a potent leukotriene B4 (LTB4) receptor antagonist, exhibiting a Ki of 2 μM in porcine neutrophil membranes. This compound effectively inhibits LTB4-induced chemotaxis and calcium flux in isolated human neutrophils, with IC50 values of 10 μM and 7 μM, respectively. Additionally, ricinelaidic acid demonstrates the ability to mitigate bronchoconstriction induced by LTB4 in rat models, making it a valuable reagent for studying inflammatory processes and potential therapeutic interventions in respiratory conditions.
Chemical Information
| Catalog Num | A61092 |
|---|---|
| M. Wt | 298.46 |
| Formula | C18H34O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 540-12-5 |
| Synonyms | |
| SMILES | OC(CCCCCCC/C=C/C[C@H](O)CCCCCC)=O |
Biological Activity
| Description | Ricinelaidic acid is a potent leukotriene B4 (LTB4) receptor antagonist, exhibiting a Ki of 2 μM in porcine neutrophil membranes. This compound effectively inhibits LTB4-induced chemotaxis and calcium flux in isolated human neutrophils, with IC50 values of 10 μM and 7 μM, respectively. Additionally, ricinelaidic acid demonstrates the ability to mitigate bronchoconstriction induced by LTB4 in rat models, making it a valuable reagent for studying inflammatory processes and potential therapeutic interventions in respiratory conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
