Product Data Sheet
CysLT1 receptor antagonist-1
Catalog No. A61108
CysLT1 receptor antagonist-1 is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1R), exhibiting an IC50 value of 3.9 µM. This compound demonstrates weak agonistic activity against the G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficacy of 23% at 10 µM. CysLT1 receptor antagonist-1 is primarily utilized in research related to asthma and allergic diseases, aiding in the exploration of therapeutic interventions targeting these conditions.
Chemical Information
| Catalog Num | A61108 |
|---|---|
| M. Wt | 293.32 |
| Formula | C18H15NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 119515-00-3 |
| Synonyms | |
| SMILES | O=C(C1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1)OC |
Biological Activity
| Description | CysLT1 receptor antagonist-1 is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1R), exhibiting an IC50 value of 3.9 µM. This compound demonstrates weak agonistic activity against the G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficacy of 23% at 10 µM. CysLT1 receptor antagonist-1 is primarily utilized in research related to asthma and allergic diseases, aiding in the exploration of therapeutic interventions targeting these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
