Product Data Sheet
YM158 free base
Catalog No. A61114
YM158 free base is a potent and selective antagonist of the leukotriene D4 (LTD4) and thromboxane A2 (TXA2) receptors, exhibiting pA2 values around 8.87 and 8.81, respectively. This compound effectively modulates inflammatory responses and is valuable for research applications related to respiratory diseases, cardiovascular conditions, and allergy-related studies. Its specificity makes it an important tool for examining the roles of leukotriene and thromboxane signaling in various biological processes.
Chemical Information
| Catalog Num | A61114 |
|---|---|
| M. Wt | 681.22 |
| Formula | C32H33ClN6O5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 179102-65-9 |
| Synonyms | YM-57158 |
| SMILES | O=C(NC1=CC(CCCS(=O)(C2=CC=C(Cl)C=C2)=O)=CC=C1OCC3=NN=NN3)C4=CC=CC(OCC5=NC(C(C)(C)C)=CS5)=C4 |
Biological Activity
| Description | YM158 free base is a potent and selective antagonist of the leukotriene D4 (LTD4) and thromboxane A2 (TXA2) receptors, exhibiting pA2 values around 8.87 and 8.81, respectively. This compound effectively modulates inflammatory responses and is valuable for research applications related to respiratory diseases, cardiovascular conditions, and allergy-related studies. Its specificity makes it an important tool for examining the roles of leukotriene and thromboxane signaling in various biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
