Product Data Sheet
BMS-520
Catalog No. A61195
BMS-520 is a selective sphingosine-1-phosphate 1 (S1P1) agonist with an EC50 of 0.47 nM, exhibiting approximately 3400-fold selectivity over S1P3. This compound has been shown to possess significant efficacy in models of arthritis and experimental autoimmune encephalomyelitis (EAE), making it valuable for research in autoimmune diseases. BMS-520 is a promising tool for studying the therapeutic potential of S1P1 modulation in various inflammatory conditions.
Chemical Information
| Catalog Num | A61195 |
|---|---|
| M. Wt | 470.40 |
| Formula | C23H17F3N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1236188-38-7 |
| Synonyms | |
| SMILES | O=C(O)C1CN(C1)CC2=CC=C(C=C2)C3=NOC(C4=C(C(C5=CC=CC=C5)=NO4)C(F)(F)F)=N3 |
Biological Activity
| Description | BMS-520 is a selective sphingosine-1-phosphate 1 (S1P1) agonist with an EC50 of 0.47 nM, exhibiting approximately 3400-fold selectivity over S1P3. This compound has been shown to possess significant efficacy in models of arthritis and experimental autoimmune encephalomyelitis (EAE), making it valuable for research in autoimmune diseases. BMS-520 is a promising tool for studying the therapeutic potential of S1P1 modulation in various inflammatory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
