Product Data Sheet
GSK2018682 hydrochloride
Catalog No. A61196
GSK2018682 hydrochloride is a specific agonist for the sphingosine-1-phosphate receptors S1P1 and S1P5, exhibiting pEC50 values of 7.7 and 7.2, respectively. It shows no agonist activity toward the S1P2, S1P3, or S1P4 receptors. This compound is primarily utilized in research investigating multiple sclerosis and related neurological disorders, offering insights into the modulation of immune responses and vascular integrity.
Chemical Information
| Catalog Num | A61196 |
|---|---|
| M. Wt | 477.34 |
| Formula | C22H22Cl2N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1034687-52-9 |
| Synonyms | |
| SMILES | O=C(CCCN1C=CC2=C(C3=NOC(C4=CC(Cl)=C(OC(C)C)N=C4)=N3)C=CC=C21)O.Cl |
Biological Activity
| Description | GSK2018682 hydrochloride is a specific agonist for the sphingosine-1-phosphate receptors S1P1 and S1P5, exhibiting pEC50 values of 7.7 and 7.2, respectively. It shows no agonist activity toward the S1P2, S1P3, or S1P4 receptors. This compound is primarily utilized in research investigating multiple sclerosis and related neurological disorders, offering insights into the modulation of immune responses and vascular integrity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
