Product Data Sheet
BMS-986104
Catalog No. A61222
BMS-986104 is a selective modulator of the S1P1 receptor, exhibiting significant biological activity in promoting remyelination. It demonstrates efficacy in a mouse model of experimental autoimmune encephalomyelitis (EAE), showing comparable results to established agents. Mechanistically, BMS-986104 effectively facilitates remyelination in a three-dimensional brain cell culture assay involving lysophosphatidylcholine-induced demyelination, making it a valuable tool for research on neurodegenerative diseases and myelin repair mechanisms.
Chemical Information
| Catalog Num | A61222 |
|---|---|
| M. Wt | 329.52 |
| Formula | C22H35NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1622180-31-7 |
| Synonyms | |
| SMILES | OC[C@@]1(C[C@@](CC1)([H])C2=CC=C(C[C@@H](CC3)CCCCCC)C3=C2)N |
Biological Activity
| Description | BMS-986104 is a selective modulator of the S1P1 receptor, exhibiting significant biological activity in promoting remyelination. It demonstrates efficacy in a mouse model of experimental autoimmune encephalomyelitis (EAE), showing comparable results to established agents. Mechanistically, BMS-986104 effectively facilitates remyelination in a three-dimensional brain cell culture assay involving lysophosphatidylcholine-induced demyelination, making it a valuable tool for research on neurodegenerative diseases and myelin repair mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
