Product Data Sheet
Telenzepine
Catalog No. A61372
Telenzepine is an antimuscarinic agent that selectively targets muscarinic receptors, demonstrating binding affinities with Kis of 0.94 nM for M1 mAChR and 17.8 nM for M2 mAChR. It effectively inhibits synaptic transmission induced by muscarinic or M1 receptor agonists, resulting in a reduction of extracellular slow excitatory postsynaptic potentials with an EC50 of 38 nM and slow inhibitory postsynaptic potentials with an EC50 of 253 nM. This compound is valuable for research in neuropharmacology and the study of cholinergic signaling pathways.
Chemical Information
| Catalog Num | A61372 |
|---|---|
| M. Wt | 370.47 |
| Formula | C19H22N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 80880-90-6 |
| Synonyms | |
| SMILES | O=C1C2=CSC(C)=C2N(C(CN3CCN(C)CC3)=O)C4=CC=CC=C4N1 |
Biological Activity
| Description | Telenzepine is an antimuscarinic agent that selectively targets muscarinic receptors, demonstrating binding affinities with Kis of 0.94 nM for M1 mAChR and 17.8 nM for M2 mAChR. It effectively inhibits synaptic transmission induced by muscarinic or M1 receptor agonists, resulting in a reduction of extracellular slow excitatory postsynaptic potentials with an EC50 of 38 nM and slow inhibitory postsynaptic potentials with an EC50 of 253 nM. This compound is valuable for research in neuropharmacology and the study of cholinergic signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
