Product Data Sheet

Bibn 140

Catalog No. A61378

main product photo
Bibn 140 is a pyridine derivative that acts as a selective antagonist of the M2 muscarinic acetylcholine receptor (mAChR), exhibiting high affinity with a Ki value of 12 nM. This compound is primarily utilized in research exploring cholinergic signaling and its implications in neurological disorders. Its specificity for the M2 subtype over the M1 receptor positions it as a valuable tool for studying M2 receptor-related biological processes.
Chemical Information
Catalog NumA61378
M. Wt532.72
FormulaC32H44N4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.145301-79-7
Synonyms
SMILESCCCC(C)(C(N(CC)CCCC1CCN(CC1)CC(N(C2=CC=CC=C2N3)C4=CC=CC=C4C3=O)=O)=O)C
Biological Activity
DescriptionBibn 140 is a pyridine derivative that acts as a selective antagonist of the M2 muscarinic acetylcholine receptor (mAChR), exhibiting high affinity with a Ki value of 12 nM. This compound is primarily utilized in research exploring cholinergic signaling and its implications in neurological disorders. Its specificity for the M2 subtype over the M1 receptor positions it as a valuable tool for studying M2 receptor-related biological processes.
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