Product Data Sheet
Lu AE51090
Catalog No. A61395
Lu AE51090 is a selective agonist of the muscarinic M1 receptor, designed to penetrate the blood-brain barrier. This compound activates the human M1 receptor with an EC50 of 61 nM and demonstrates minimal activity at M2 to M5 receptors. Lu AE51090 has been shown to produce procognitive effects in murine models and is relevant for research into Alzheimer’s disease and cognitive impairments associated with schizophrenia.
Chemical Information
| Catalog Num | A61395 |
|---|---|
| M. Wt | 407.51 |
| Formula | C24H29N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1186229-95-7 |
| Synonyms | |
| SMILES | O=C(NC1CCN(CCCN2C3=CC=CC=C3OCC2=O)CC1)CC4=CC=CC=C4 |
Biological Activity
| Description | Lu AE51090 is a selective agonist of the muscarinic M1 receptor, designed to penetrate the blood-brain barrier. This compound activates the human M1 receptor with an EC50 of 61 nM and demonstrates minimal activity at M2 to M5 receptors. Lu AE51090 has been shown to produce procognitive effects in murine models and is relevant for research into Alzheimer’s disease and cognitive impairments associated with schizophrenia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
