Product Data Sheet
Anagyrine hydrochloride
Catalog No. A61398
Anagyrine hydrochloride is a quinolizidine alkaloid that serves as a desensitizer of nicotinic acetylcholine receptors (nAChR). It exhibits potent binding to muscarinic acetylcholine receptors with an IC50 value of 132 µM and a weaker interaction with nAChR at 2096 µM. This compound effectively desensitizes nAChR without requiring metabolic conversion, making it valuable for research involving cholinergic signaling and receptor function studies.
Chemical Information
| Catalog Num | A61398 |
|---|---|
| M. Wt | 280.79 |
| Formula | C15H21ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 74195-83-8 |
| Synonyms | (-)-Anagyrine hydrochloride; Monolupine hydrochloride; Rhombinine hydrochloride |
| SMILES | O=C1N2C([C@]3([H])C[C@]([C@]4([H])N(CCCC4)C3)([H])C2)=CC=C1.Cl |
Biological Activity
| Description | Anagyrine hydrochloride is a quinolizidine alkaloid that serves as a desensitizer of nicotinic acetylcholine receptors (nAChR). It exhibits potent binding to muscarinic acetylcholine receptors with an IC50 value of 132 µM and a weaker interaction with nAChR at 2096 µM. This compound effectively desensitizes nAChR without requiring metabolic conversion, making it valuable for research involving cholinergic signaling and receptor function studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
