Product Data Sheet
Trihexyphenidyl
Catalog No. A61408
Trihexyphenidyl is a selective M1 muscarinic receptor antagonist, with an IC50 of 3.7 nM for rat cerebral cortex M1 receptors. It modulates cholinergic activity, effectively countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl is utilized in research for Parkinson's disease and demonstrates efficacy in improving movement disorders, as well as inhibiting vagally-induced bradycardia and vasodilation. Its inhibition of McN-A-343-induced pressor responses highlights its potential in studying neurophysiological effects.
Chemical Information
| Catalog Num | A61408 |
|---|---|
| M. Wt | 301.47 |
| Formula | C20H31NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 144-11-6 |
| Synonyms | |
| SMILES | OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCCC3 |
Biological Activity
| Description | Trihexyphenidyl is a selective M1 muscarinic receptor antagonist, with an IC50 of 3.7 nM for rat cerebral cortex M1 receptors. It modulates cholinergic activity, effectively countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl is utilized in research for Parkinson's disease and demonstrates efficacy in improving movement disorders, as well as inhibiting vagally-induced bradycardia and vasodilation. Its inhibition of McN-A-343-induced pressor responses highlights its potential in studying neurophysiological effects. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
