Product Data Sheet
Lu 26-046
Catalog No. A61437
Lu 26-046 is a selective agonist for the muscarinic M1 and M2 receptors, with reported affinities (Ki values) of 0.51 nM and 26 nM, respectively, while exhibiting weak antagonistic activity at the M3 receptor (Ki 5 nM). This compound demonstrates a specific stimulating effect that has been recognized in behavioral assays with rats. Lu 26-046 serves as a valuable tool in research investigating cholinergic signaling pathways and receptor subtype functions.
Chemical Information
| Catalog Num | A61437 |
|---|---|
| M. Wt | 208.28 |
| Formula | C10H12N2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 143756-51-8 |
| Synonyms | |
| SMILES | C#CCOC1=NSC2=C1CNC[C@H]2C |
Biological Activity
| Description | Lu 26-046 is a selective agonist for the muscarinic M1 and M2 receptors, with reported affinities (Ki values) of 0.51 nM and 26 nM, respectively, while exhibiting weak antagonistic activity at the M3 receptor (Ki 5 nM). This compound demonstrates a specific stimulating effect that has been recognized in behavioral assays with rats. Lu 26-046 serves as a valuable tool in research investigating cholinergic signaling pathways and receptor subtype functions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
