Product Data Sheet

L-687306

Catalog No. A61453

main product photo
L-687306 is a high-affinity partial agonist of the muscarinic M1 receptor, demonstrating significant activity in rat ganglia. Additionally, it acts as a competitive antagonist at M2 and M3 muscarinic receptors in guinea pig cardiac and ileal tissues, respectively. This compound is valuable for investigating muscarinic receptor reserve and exploring muscarinic signaling pathways in various physiological contexts.
Chemical Information
Catalog NumA61453
M. Wt205.26
FormulaC11H15N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.133444-98-1
Synonyms
SMILES[H][C@@]12[C@@H](C3=NC(C4CC4)=NO3)C[N@](CC2)C1
Biological Activity
DescriptionL-687306 is a high-affinity partial agonist of the muscarinic M1 receptor, demonstrating significant activity in rat ganglia. Additionally, it acts as a competitive antagonist at M2 and M3 muscarinic receptors in guinea pig cardiac and ileal tissues, respectively. This compound is valuable for investigating muscarinic receptor reserve and exploring muscarinic signaling pathways in various physiological contexts.
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