Product Data Sheet
L 689660 maleate
Catalog No. A61466
L 689660 maleate is a selective agonist for M1 and M3 muscarinic receptors, exhibiting potent cholinomimetic activity. Specifically, it demonstrates full agonist properties at the M1 muscarinic receptor in the rat superior cervical ganglion with a pEC50 of 7.3. Additionally, L 689660 maleate effectively activates M3 receptors in the guinea pig ileum myenteric plexus-longitudinal muscle and trachea, with pEC50 values of 7.5 and 7.7, respectively. This compound is valuable for research applications targeting muscarinic receptor signaling pathways.
Chemical Information
| Catalog Num | A61466 |
|---|---|
| M. Wt | 339.77 |
| Formula | C15H18ClN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 144860-79-7 |
| Synonyms | |
| SMILES | ClC1=CN=CC(C2CN3CCC2CC3)=N1.O=C(/C=C\C(O)=O)O.[x] |
Biological Activity
| Description | L 689660 maleate is a selective agonist for M1 and M3 muscarinic receptors, exhibiting potent cholinomimetic activity. Specifically, it demonstrates full agonist properties at the M1 muscarinic receptor in the rat superior cervical ganglion with a pEC50 of 7.3. Additionally, L 689660 maleate effectively activates M3 receptors in the guinea pig ileum myenteric plexus-longitudinal muscle and trachea, with pEC50 values of 7.5 and 7.7, respectively. This compound is valuable for research applications targeting muscarinic receptor signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
