M3 mAChR agonist 1
Catalog No. A61485

M3 mAChR agonist 1 is a positive allosteric modulator (PAM) specifically targeting the M3 and M5 muscarinic acetylcholine receptors. This compound exhibits notable selectivity over other muscarinic subtypes, including M1, M2, and M4. M3 mAChR agonist 1 enhances the contraction of isolated rat bladder strips by modulating M3 receptor activity, thus promoting signaling pathways associated with bladder function. This reagent is suitable for research applications in endocrinology and related fields.
Chemical Information
| Catalog Num | A61485 |
|---|---|
| M. Wt | 618.67 |
| Formula | C29H33F3N6O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1624297-26-2 |
| Synonyms | |
| SMILES | O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC=C(OC)C(C(F)(F)F)=C4)=C(CN5[C@H](CC)CCC5)S3)=O)N=C2)CC1)O |
Biological Activity
| Description | M3 mAChR agonist 1 is a positive allosteric modulator (PAM) specifically targeting the M3 and M5 muscarinic acetylcholine receptors. This compound exhibits notable selectivity over other muscarinic subtypes, including M1, M2, and M4. M3 mAChR agonist 1 enhances the contraction of isolated rat bladder strips by modulating M3 receptor activity, thus promoting signaling pathways associated with bladder function. This reagent is suitable for research applications in endocrinology and related fields. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


