Product Data Sheet
BCFTP
Catalog No. A61568
BCFTP is a potent and selective positive allosteric modulator of the human Mas-related G protein-coupled receptor X1 (MrgprX1). It enhances MrgprX1 signaling in HEK293 cells and effectively alleviates neuropathic pain-related behaviors in a humanized mouse model of chronic constrictive injury, demonstrating a MrgprX1-dependent mechanism. BCFTP has the potential to synergistically enhance the analgesic effects of psychoactive substances in this model. This compound serves as a valuable tool for research into neuropathic pain mechanisms and potential therapeutics.
Chemical Information
| Catalog Num | A61568 |
|---|---|
| M. Wt | 496.90 |
| Formula | C23H17ClF4N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2781215-95-8 |
| Synonyms | |
| SMILES | CC(C)(C)C1=C(C2=CC=C(Cl)C=C2)C3=C(S1)N=CN=C3OC4=C(F)C=CC=C4OC(F)(F)F |
Biological Activity
| Description | BCFTP is a potent and selective positive allosteric modulator of the human Mas-related G protein-coupled receptor X1 (MrgprX1). It enhances MrgprX1 signaling in HEK293 cells and effectively alleviates neuropathic pain-related behaviors in a humanized mouse model of chronic constrictive injury, demonstrating a MrgprX1-dependent mechanism. BCFTP has the potential to synergistically enhance the analgesic effects of psychoactive substances in this model. This compound serves as a valuable tool for research into neuropathic pain mechanisms and potential therapeutics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
