Product Data Sheet
ZINC49534341
Catalog No. A61571
ZINC49534341 is an antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) with a binding affinity (Ki) of 32 nM. This compound negatively regulates MRGPRX2-mediated signaling pathways, demonstrating utility in research related to pain, inflammation, and mast cell activation. It serves as a valuable tool for investigating the role of MRGPRX2 in various biological processes and for potential therapeutic applications.
Chemical Information
| Catalog Num | A61571 |
|---|---|
| M. Wt | 275.35 |
| Formula | C12H9N3OS2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1274013-03-4 |
| Synonyms | |
| SMILES | O=C1N(CC2=NC=CS2)C(NC3=C1C=CC=C3)=S |
Biological Activity
| Description | ZINC49534341 is an antagonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) with a binding affinity (Ki) of 32 nM. This compound negatively regulates MRGPRX2-mediated signaling pathways, demonstrating utility in research related to pain, inflammation, and mast cell activation. It serves as a valuable tool for investigating the role of MRGPRX2 in various biological processes and for potential therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
