Product Data Sheet
Nelremagpran
Catalog No. A61572
Nelremagpran is a potent modulator of MRGPR X4, exhibiting antagonist activity with an IC50 of less than 100 nM. This compound is valuable for investigating autoimmune diseases, including psoriasis, multiple sclerosis, Stevens-Johnson syndrome, and various chronic itch conditions. Its ability to selectively inhibit MRGPR X4 makes it a crucial tool for elucidating the role of this receptor in disease pathology and for the development of targeted therapeutic strategies.
Chemical Information
| Catalog Num | A61572 |
|---|---|
| M. Wt | 348.68 |
| Formula | C15H9ClF4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2492595-24-9 |
| Synonyms | MRGPRX4 modulator-2 |
| SMILES | O=C(O)C1=CC=CC(COC2=CC=C(C(F)(F)F)C=C2Cl)=C1F |
Biological Activity
| Description | Nelremagpran is a potent modulator of MRGPR X4, exhibiting antagonist activity with an IC50 of less than 100 nM. This compound is valuable for investigating autoimmune diseases, including psoriasis, multiple sclerosis, Stevens-Johnson syndrome, and various chronic itch conditions. Its ability to selectively inhibit MRGPR X4 makes it a crucial tool for elucidating the role of this receptor in disease pathology and for the development of targeted therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
