Product Data Sheet
PSB-22034
Catalog No. A61579
PSB-22034 is a selective agonist of the MRGPRX4 receptor, demonstrating EC50 values of 11.2 nM in Ca2+ mobilization assays and 30.0 nM in β-arrestin recruitment assays. This compound is valuable for investigating the physiological roles of MRGPRX4 and its involvement in pain, neurogenic inflammation, and other pathological processes. Its precise modulation of MRGPRX4 provides a tool for elucidating receptor functions in various biological contexts.
Chemical Information
| Catalog Num | A61579 |
|---|---|
| M. Wt | 460.42 |
| Formula | C21H25N4O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2768131-22-0 |
| Synonyms | |
| SMILES | O=C1C2=C(N(C(N1CC#C)=O)CCCCP(O)(O)=O)N=C(N2)CCC3=CC(OC)=CC=C3 |
Biological Activity
| Description | PSB-22034 is a selective agonist of the MRGPRX4 receptor, demonstrating EC50 values of 11.2 nM in Ca2+ mobilization assays and 30.0 nM in β-arrestin recruitment assays. This compound is valuable for investigating the physiological roles of MRGPRX4 and its involvement in pain, neurogenic inflammation, and other pathological processes. Its precise modulation of MRGPRX4 provides a tool for elucidating receptor functions in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
