Product Data Sheet
EP-3945
Catalog No. A61593
EP-3945 is a selective agonist of the Mas-related G protein-coupled receptor (MRGPR), demonstrating greater efficacy compared to β-Alanine. This receptor is significantly involved in mediating inflammatory pruritus and pain responses. EP-3945 specifically activates the Gq signaling pathway, with an EC50 value of 211.6 nM, enabling its application in studies focused on pain modulation and itch sensation research.
Chemical Information
| Catalog Num | A61593 |
|---|---|
| M. Wt | 418.49 |
| Formula | C24H26N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3057176-00-5 |
| Synonyms | |
| SMILES | O=C(C1(CC1)C2=CC=C(OC)C=C2)N(CC3)CCC3NC(NC4=O)=NC5=C4C=CC=C5 |
Biological Activity
| Description | EP-3945 is a selective agonist of the Mas-related G protein-coupled receptor (MRGPR), demonstrating greater efficacy compared to β-Alanine. This receptor is significantly involved in mediating inflammatory pruritus and pain responses. EP-3945 specifically activates the Gq signaling pathway, with an EC50 value of 211.6 nM, enabling its application in studies focused on pain modulation and itch sensation research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
