Product Data Sheet

TC-MCH 7c

Catalog No. A61610

main product photo
TC-MCH 7c is a selective antagonist of the melanin-concentrating hormone receptor 1 (MCH1R), featuring a phenylpyridone structure. This compound demonstrates high potency with an IC50 of 5.6 nM for human MCH1R, alongside Kis of 3.4 nM and 3.0 nM for human and mouse MCH1R, respectively. TC-MCH 7c is designed for oral administration and effectively penetrates the brain, making it a valuable tool for research in neurological disorders and metabolic regulation.
Chemical Information
Catalog NumA61610
M. Wt408.47
FormulaC24H25FN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.864756-35-4
Synonyms
SMILESO=C1N(C=CC(OCC2=CC=C(F)C=C2)=C1)C3=CC=C(OCCN4CCCC4)C=C3
Biological Activity
DescriptionTC-MCH 7c is a selective antagonist of the melanin-concentrating hormone receptor 1 (MCH1R), featuring a phenylpyridone structure. This compound demonstrates high potency with an IC50 of 5.6 nM for human MCH1R, alongside Kis of 3.4 nM and 3.0 nM for human and mouse MCH1R, respectively. TC-MCH 7c is designed for oral administration and effectively penetrates the brain, making it a valuable tool for research in neurological disorders and metabolic regulation.
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SHIPPING AND STORAGE
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